This whitepaper delves into the transformative impact of 3D-based simulation training in healthcare education, comparing it against traditional learning methods. Through a comprehensive analysis that includes a historical overview, theoretical frameworks, and real-world case studies, this document evaluates the effectiveness of these modern educational tools in enhancing knowledge retention, skill acquisition, and clinical application. It addresses the challenges and opportunities of integrating 3D simulations into healthcare curricula, offering insights for educators, policymakers, and technology developers on navigating this evolving landscape.